Sunday 18 December 2011

Resolving controversies on the path to Alzheimer’s therapeutics

Resolving controversies on the path to Alzheimer’s therapeutics
The full text of this article is available at the link.
It's interesting to see how the research has progressed and where it may be going.

I found the time line of Alzheimer's research interesting as well as chart showing the Hypothetical time course of AD with the stages at which interventions Clinical trials are applicable. Confirms my opinion we need to act before symptoms of any kind are apparent and the distinction between normal ageing and Alzheimer's is not as clear cut as some would like to portray.

Mitochondria, Amyloid β, and Alzheimer's Disease

Mitochondria, Amyloid β, and Alzheimer's Disease
Nice free full text online paper that fits in with much of what I've been thinking about.

for those who are interested in learning how to ensure an ongoing supply of new healthy mitochondria this paper has some practical suggestions.
Mitochondrial Energetics and Therapeutics

Melatonin in Mitochondrial Dysfunction and Related Disorders

I should perhaps give a warning that these are quite heavy going papers so don't expect to understand every word initially.